院系详细页面

[外文期刊] Analysis of the key intermediates for the regioselectivity control in the methylation of the manufacture of clarithromycin by reversed-phase high performance liquid chromatography CA

作者： Liang, Jianhua¹;Yao, Guowei¹;Zheng, Shaojun¹; （¹School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, China）

出处： Chinese Journal of Chromatography (Se Pu) 2004 Vol.22 No.3 P237-240

摘要： 2′, 4″-O-Bis (trimethylsilyl) erythromycin A-9-O-(1- isopropoxycyclohexyl) oxime (2′, 4″-TMS-EMIPCH) and 2′, 4″-O-bis (trimethylsilyl)-6-O-methyleryth ...

[中文期刊] Comparative Process for the Preparation of 9-Oxime Erythromycin A CA 剑桥核

作者：孙京国，姚国伟，欧育湘（School of Material Science and Engineering, Beijing Institute of Technology, Beijing 100081, China；School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, China；College of Chemistry, Hebei Normal University, Shijiazhuang, H；School of Life Science and Technology, Beijing Institute of Technology, Beijing 100081, China；School of Material Science and Engineering, Beijing Institute of Technology, Beijing 100081, China）

出处：北京理工大学学报：英文版 2004 第1期 P76-79

关键词： oxime；erythromycin；A；synthetic；process；comparison

摘要： The comparative process for preparing 9-oxime erythromycin A (EMAO) is investigated. EMAO was synthesized and compared by the reaction of erythromycin ...

[中文期刊] Efficient and Stereoselective Synthesis of C-(β-2\'-Deoxynucleosides) CA 核源

作者： WU Qin-Pei，REES B.Colin （School of Life Science, Beijing Institute of Technology, Beijing 100081；King\'s College, London, WC2R 2LS, UK）

出处：有机化学 2004 第s1期 P27-28

摘要： The formation of triplex DNA is, in principle, an effective way of regulating the expression of selected genes.\'(1)\'Many cytosine mimics were invest ...

[中文期刊] New Cell Viability Measurement of SH-SY5Y Cells in the PDResearch-Alamarblue^TM CA 剑桥核

作者：邓玉林，牛逦原（School of Life Science and Technology Beijing Institute of Technology；Beijing 100081；China；China）

出处：北京理工大学学报(英文版) 2004 第13卷第A1期 P98-103

关键词： alamarblue?cellmodel；PDresearch

摘要： The traditional MTT assay requires destructive analyses and is not convenient in continuous monitory of cell viability. However, a new cell model was ...

[中文会议论文] 免疫荧光法检测DAT在SH-SY5Y细胞中的分布

作者：李勤，索丽松，谢海燕，张耀阳，邓玉林（北京理工大学生命科学与技术学院生物医学工程系）

出处：第六届全国光生物学学术研讨会中国海南三亚 2004

会议录：第六届全国光生物学学术研讨会论文集 , 2004 年

摘要：帕金森病是一种中老年期常见的慢性、进行性神经系统变性疾病,是中老年常见的致残疾病之一,严重影响到患者的健康和生存能力。其主要的病理变化是黑质致密部(SNc)多巴胺(dopamine,DA)能神经元进行性变性死亡,残存神经元多巴胺合成能力降低,从而对锥体外系的运动调节功能下降。多巴胺转运蛋白(dopa ...

[中文期刊] 生物系统的发光原理及其应用核

作者：李勤（北京理工大学生命科学与技术学院生物医学工程系　　北京　　（100081））

出处：生命科学仪器 2004 第2卷第4期 P33-37

关键词：生物发光；荧光；化学发光；超微弱光子辐射

摘要：与生物系统相关的发光是研究生命现象的重要信息,体现了生物体的生命状态.通过对荧光信号、化学发光信号或超微弱光子辐射的探测,可以了解生物体内在的特点.本文对生物系统的发光原理和不同种类生物发光的应用领域进行了简单概述.随着光电检测技术的进步,生物发光将会得到更加深入的研究和推广,在发光机理和技术应用方 ...

[中文期刊] Separation of Felted Explosives by Pressurized Mic CA 核源

作者： Jing JIANG，Su Xuan GONG，Hu Wei LIU，Yong ZHANG，Yu Lin DENG，Jun Ling GU，Ai Qin LUO，Li Xin WANG （Jing Jiang(Chemistry Department,School of Sciences,Beijing Institute of Technology ,Beijing 100081)；Su Xuan GONG(College of Chemistry and Molecular Engineering,Peking University ,Beijing 100871)；Hu Wei LIU(Institute of Applied Chemistry,Chinese Academy of Engineering Physics ,Mianyang 621900)；Yong ZHANG(School of Life Science and Technology,Beijing Institute of Technology ,Beijing 100081)）

出处：中国化学快报(英文版) 2004 第7期 P831-833

关键词： Felted；explosives；microemulsion；electrokinetic；chromatography；(MEEKC)；separation；pressurized；MEEKC

摘要： A new MEEKC method assisted with pressure-driven mobile phase was presented for the separation of felted explosives. Microemulsion solution was compos ...

[中文期刊] Capillary Column Coated with Heptakis(2,3, 6-tri-O-octyl)-β-cyclodextrin Using Sol-gel Technology CA 核源

作者： Xiao Xia GE，Ruo Nong FU，Rong Ji DAI，Li Wen LIU，Mei Ling QI （Xiao Xia GE(Department of chemistry school of science, Beijing institute of technology, Beijing 100081) Ruo Nong FU(School of life and technology Beijing, institute of technology, Beijing 100081)）

出处： Chinese Chemical Letters 2004 第4期 P428-430

关键词： Heptakis(2,3,6-tri-O-octy1)-β-cyclodextrin；capillary；gas；chromatography；sol-gel；technology.

摘要： Heptakis(2, 3, 6-tri-O-octyl)-β-cyclodextrin was coated onto the fused silica capillary by sol-gel technology. Column efficiency and column selectivit ...

[中文期刊] Synthesis of Amino Acid Derived β-Cyclodextrins Used in Chiral Separation by Capillary Electrophoresis CA 剑桥核

作者：戴荣继，佟斌，魏征，顾峻岭，邓玉林，李明愉，傅若农（School of Life Science and Technology, Beijing Institute of Technology, Beijing100081, China ,School of Material Science and Engineering, Beijing Institute of Technology, Beijing100081, China ,School of Life Science and Technology, Beijing Institute of Technology, Beijing100081, China ,School of Science, Beijing Institute of Technology, Beijing100081, China ,School of Life Science and Technology, Beijing Institute of Technology, Beijing100081, China ,School of Mechatronics Engineering, Beijing Institute of Technology, Beijing 100081, China ,School of Science, Beijing Institute of Technology, Beijing100081, China）

出处：北京理工大学学报：英文版 2004 第2期 P206-209

关键词： cyclodextrin；derivatives；capillary；electrophoresis；chiral；selector

摘要： Six new kinds of amino acid derived β-cyclodextrins were synthesized to improve their water solubility and chiral separation properties. They are hept ...

[中文期刊] 数字化高灵敏度荧光显微镜在As₂O₃诱导MGC-803细胞核凋亡产生钙振荡研究中的应用核

作者：李勤，马瑜，俞信，曹恩华，陈艾（北京理工大学生命科学与技术学院生物医学工程系　　北京　　（100081）；北京理工大学信息科学技术学院光电工程系　　北京　　（100081）；中国科学院生物物理研究所　　北京　　（100101）；中国科学院生物物理研究所　　北京　　（100101））

出处：生命科学仪器 2004 第3期 P18-21

关键词：数字化高灵敏度荧光显微镜；钙振荡；细胞核凋亡；As2O3

摘要：利用数字化高灵敏度荧光显微镜对As2O3诱导MGC-803细胞核凋亡过程中的钙振荡进行研究,通过图像中荧光强度随时间变化的规律反应钙振荡的频率和强度变化。结果证实As2O3诱导MGC-803细胞核凋亡过程中,的确引发了钙振荡,说明核钙参与了凋亡过程,并且钙振荡的频率以低频为主。对两相邻细胞核的钙振荡 ...