作者： Limin Zhang;Zhenqi Jiang;Xi Yang;Yixia Qian;Minxuan Wang;Shang Wu;Lingyun Li;Fei Jia;Zihua Wang;Zhiyuan Hu;Minzhi Zhao;Xiaoying Tang;Gang Li;Hanbing Shang;Xiaoyuan Chen;Weizhi Wang （¹ Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Key Laboratory of Cluster Science of Ministry of Education, Beijing Key Laboratory of Photoelectronic/Electro-photonic Conversion Materials, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China. ² School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, P.R. China. ³ Cancer Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, P. R. China. ⁴ CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Beijing, 100190, P. R. China. ⁵ Centre for Neuroscience Research, School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, 350108, P. R. China. ⁶ Gastrointestinal Surgery, Shanxi Hospital of Traditional Chinese Medicine, Taiyuan, 030012, P. R. China. ⁷ Department of Surgery, Ruijin Hospital, Shanghai Jiaotong University, Shanghai, 200025, P. R. China. ⁸ Engineering, Yong Loo Lin School of Medicine and Faculty of Engineering, National University of Singapore, Singapore, 119074, Singapore. ⁹ Clinical Imaging Research Centre, Centre for Translational Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. ¹⁰ Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore.）

出处： Advanced materials (Deerfield Beach, Fla.) 0 Vol.35 No.2 Pe2207330

关键词： combination therapy;immune checkpoints;peptide self-assembly;screening.

摘要： Immune checkpoint blockade combined with reversal of the immunosuppressive tumor microenvironment (TME) can dramatically enhance anti-tumor immunity, ...