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[中文会议论文] 多模式毛细管电泳核酸适配体筛选策略研究

作者：屈锋，杨歌，胡猷浩，魏强（北京理工大学生命学院）

出处： 2016全国生命分析化学学术大会南京 2016

关键词：核酸适配体；筛选策略；毛细管电泳；CE-SELEX

摘要：核酸适配体可作为生物分析、食品和环境检测的探针，并在疾病诊断和治疗、药物研发和分子成像领域具有广阔的应用空间和产生经济效益的巨大潜力。目前的适配体远未发挥潜能。筛选复杂，成本高，效率低是其应用受限的瓶颈之一。

[中文会议论文] 制备L-半胱氨酸修饰的硫化锌量子点荧光检测牛血红蛋白

作者：张鑫，杨戍，谢白羿，姜锐，孙立权，罗爱芹（北京理工大学生命学院）

出处：中国化学会第十一届全国生物医药色谱及相关技术学术交流会中国江西井冈山 2016

会议录：中国化学会第十一届全国生物医药色谱及相关技术学术交流会（大会特邀报告及墙报）论文摘要集

关键词： L-半胱氨酸；硫化锌量子点；牛血红蛋白；荧光检测

摘要：量子点（quantum dots,QDs）是一种由II-VI,III-V或IV-VI族元素制备的半导体纳米结构材料,在三维空间结构上呈纳米尺寸,粒径一般为1-10nm。由于其独特的光学性质,如量子产率高,发射波长随颗粒尺寸大小可变,稳定性高,窄而对称的发射光谱以及斯托克斯位移大,量子点在生化分析、生 ...

[外文期刊] Rapid Isolation and Determination of Flavones in Biological Samples Using Zinc Complexation Coupled with High-Performance Liquid Chromatography SCIE

作者： Sun, Chenghe;Wang, Hecheng;Wang, Yingping;Xiao, Shengyuan （Institute of Special Wild Animals and Plants, Chinese Academy of Agricultural Science, Changchun 130122, China. 18611297241@126.com. School of Life Science, Beijing Institute of Technology, Beijing 100081, China. 18611297241@126.com. Institute of Special Wild Animals and Plants, Chinese Academy of Agricultural Science, Changchun 130122, China. whcxf332@163.com. School of Life Science, Beijing Institute of Technology, Beijing 100081, China. whcxf332@163.com. Institute of Special Wild Animals and Plants, Chinese Academy of Agricultural Science, Changchun 130122, China. yingpingw@126.com. Institute of Special Wild Animals and Plants, Chinese Academy of Agricultural Science, Changchun 130122, China. xiaoshengyuan@tsinghua.org.cn. School of Life Science, Beijing Institute of Technology, Beijing 100081, China. xiaoshengyuan@tsinghua.org.cn.）

出处： Molecules 2016 Vol.21 No.8 P21081067,2-12

关键词： Scutellaria baicalensis;dried blood spot;metal complexation;high-performance liquid chromatography;chlorophyll;heme

摘要： Chlorophyll-type contaminants are commonly encountered in the isolation and determination of flavones of plant aerial plant parts. Heme is also a diff ...

[中文期刊] 纳米技术瞄准疾病诊疗源

作者：李彦辉，江兆潭，庆宏（北京理工大学生命学院）

出处：生命科学仪器 2016 第14卷第1-2期 P18-22

关键词：纳米技术；纳米生物医学；纳米诊断；纳米毒理

摘要：近年,生物学、医学与纳米科学交叉融合催生的纳米生物医学领域获得快速发展,实现了从纳米视角对物质结构的精确控制,为现代生物医学的相关研究提供了新颖独到的医学思维和医学技术。本文主要对纳米生物医学技术在疾病诊断治疗等方面的研究近况及取得的成就进行了综述。了解纳米技术在这些医学领域的研究及应用现状,对于更 ...

[中文期刊] 基于核酸的高灵敏蛋白质检测方法研究进展源

作者：李昱，代唯强，吕雪飞（北京理工大学生命学院）

出处：生命科学仪器 2016 第14卷第5-6期 P25-29

关键词：核酸；高灵敏度；蛋白质检测

摘要：生物标志物的超灵敏检测对于疾病的早期精准诊断和治疗起到了至关重要的作用,基于核酸的高灵敏度蛋白检测方法由于核酸的易合成、易修饰和可扩增的特点受到科研人员的广泛关注.本文综述了几种基于核酸的高灵敏度蛋白检测方法,诸如免疫聚合酶链式反应、免疫滚环扩增反应、邻位连接技术等,及其优缺点,并对其未来的发展方向 ...

[外文期刊] Correction: Ion collision cross section analyses in quadrupole ion traps using the filter diagonalization method: a theoretical study

作者： Ting Jiang[a];Muyi He[a];Dan Guo[a];Yanbing Zhai[a];Wei Xu;[a][b] （School of Life Science, Beijing Institute of Technology Haidian, Beijing 100081, China. weixu@bit.edu.cn. School of Life Science, Beijing Institute of Technology Haidian, Beijing 100081, China. weixu@bit.edu.cn. School of Life Science, Beijing Institute of Technology Haidian, Beijing 100081, China. weixu@bit.edu.cn. School of Life Science, Beijing Institute of Technology Haidian, Beijing 100081, China. weixu@bit.edu.cn. School of Life Science, Beijing Institute of Technology Haidian, Beijing 100081, China. weixu@bit.edu.cn and Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, The Ministry of Industry and Information Technology, Beijing Institute of Technology, Beijing 100081, China.）

出处： PCCP: Physical Chemistry Chemical Physics 2016 Vol.18 No.42 P29642

摘要： Correction for ‘Ion collision cross section analyses in quadrupole ion traps using the filter diagonalization method: a theoretical study’ by Ting Jia ...

[外文期刊] Myricitrin Attenuates High Glucose-Induced Apoptosis through Activating Akt-Nrf2 Signaling in H9c2 Cardiomyocytes SCIE

作者： Zhang, Bin;Chen, Yaping;Shen, Qiang;Liu, Guiyan;Ye, Jingxue;Sun, Guibo;Sun, Xiaobo （Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. zhangbin7@126.com./Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China. zhangbin7@126.com./Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Beijing 100193, China. zhangbin7@126.com./Key Laboratory of Efficacy Evaluation of Chinese Medicine against Glyeolipid Metabolism Disorder Disease, State Administration of Traditional Chinese Medicine, Beijing 100193, China. zhangbin7@126.com. School of Life Science, Beijing Institute of Technology, Beijing 100081, China. Yp_chen@yeah.net. Center of Research and Development on Life Sciences and Environmental Sciences, Harbin University of Commerce, Harbin 150076, China. jinqilinsq@163.com. School of Life Science, Beijing Institute of Technology, Beijing 100081, China. gyliu@bit.edu.cn. Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. yejingxue2002@126.com./Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China. yejingxue2002@126.com./Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Beijing 100193, China. yejingxue2002@126.com./Key Laboratory of Efficacy Evaluation of Chinese Medicine against Glyeolipid Metabolism Disorder Disease, State Administration of Traditional Chinese Medicine, Beijing 100193, China. yejingxue2002@126.com. Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. sunguibo@126.com./Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China. sunguibo@126.com./Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Beijing 100193, China. sunguibo@126.com./Key Laboratory of Efficacy Evaluation of Chinese Medicine against Glyeolipid Metabolism Disorder Disease, State Administration of Traditional Chinese Medicine, Beijing 100193, China. sunguibo@126.com. Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100193, China. sunsubmit@163.com./Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100193, China. sunsubmit@163.com./Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Beijing 100193, China. sunsubmit@163.com./Key Laboratory of Efficacy Evaluation of Chinese Medicine against Glyeolipid Metabolism Disorder Disease, State Administration of Traditional Chinese Medicine, Beijing 100193, China. sunsubmit@163.com.）

出处： Molecules 2016 Vol.21 No.7 P21070880,2-13

关键词： hyperglycemia;oxidative stress;reactive oxygen species;apoptosis;H9c2 cell

摘要： Hyperglycemia, as well as diabetes mellitus, has been shown to trigger cardiac cell apoptosis. We have previously demonstrated that myricitrin prevent ...

[中文会议论文] Construction and biomedical application of leukocyte membranes based biomimetic magnetosomes

作者： Qianmei Zhang，Fan Zhang，Jin Xu，Ke Xiong，Dongxu Zhao，Wei Wei，Guanghui Ma，Haiyan Xie （School of Life Science，Beijing Institute of Technology，Beijing 100081，P.R.China；State Key Laboratory of Biochemical Engineering，Institute of Process Engineering，Chinese Academy of Sciences Beijing 100190，P.R.China）

出处：中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议 2016

会议录：中国微米纳米技术学会纳米科学技术分会第四届年会暨2016国际纳米生物与医学学术会议论文集

关键词： leukocyte membranes；biomimetic magnetosomes；circulating tumor cells；siRNA delivery；artificial antigen presenting cell

摘要： Natural cellular membrane-based biomimetic nanoparticles have gained widespread attention owing to their cell surface mimetic characteristics and tail ...

[中文会议论文] A novel sucrose-regulatory MADS-box transcription factor GmNMHC5 promotes root development and nodulation in soybean (Glycine max [L.] Merr.)

作者： Wei Liu，Xiangdong Han，Ge Zhan，Zhenfang Zhao，Cunxiang Wu，Yongjun Feng （The National Key Facility for Crop Gene Resources and Genetic Improvement / MOA Key Lab of Soybean Biology (Beijing)，Institute of Crop Sciences，Chinese Academy of Agricultural Sciences，Beijing 100081，China；The National Key Facility for Crop Gene Resources and Genetic Improvement / MOA Key Lab of Soybean Biology (Beijing)，Institute of Crop Sciences，Chinese Academy of Agricultural Sciences，Beijing 100081，China；School of Life Science，Beijing Institute of Technology，Beijing 100081，China；School of Life Science，Beijing Institute of Technology，Beijing 100081，China）

出处：第七届国际作物科学大会 2016

会议录：第七届国际作物科学大会论文集

关键词： Glycine max；GmNMHC5；Lateral roots development；MADS-box protein；Nodule building

摘要： The MADS-box protein family includes a great number of transcription factors that all have a DNA-binding MADS-box domain.The proteins in this family w ...

[中文会议论文] BOLD Responses Induced by Acupuncture involving with GABA Modulation using MEGA-PRESS 1H-MRS

作者： Jiliang Fang，Yanping Zhao，Guiyong Liu，Xiaoling Wang，Feng Feng，Bingzhen Lei，Yong Zhang，Yuanyuan Chen，Caixia Fu，Tianyi Qian （Guang An Men Hospital，China Academy of Chinese Medical Sciences，Beijing，China；Peking Union Hospital，Peking Union Medical University，Beijing，China；School of Life Science，Beijing Institute of Technology，Beijing，China；Siemens Shenzhen Magnetic Resonance Ltd.APPL，Shenzhen，China；Siemens Healthcare，MR Collaboration NE Asia，Beijing，China）

出处： 2016中国医师协会中西医结合医师大会 2016

会议录： 2016中国医师协会中西医结合医师大会论文集

关键词： BOLD-fMRI；MEGA-PRESS 1H-MRS；acupuncture；γ-aminobutyric acid (GABA)

摘要： Objective: We aimed to compare BOLD response during acupuncture stimulation in normal subjects to investigate the neurotransmitter basis of acupunctur ...