作者： Mao, Y. F.¹;Zhang, H. L.¹;Yuan, J. H.¹;Hao, X. L.¹;Xing, J. C.¹;Xin, J. G.¹;Jiang, Y.¹ （¹ Beijing Inst Technol, Sch Optoelect, Beijing 100081, Peoples R China.）

出处： LASER PHYSICS LETTERS 2016 Vol.13 No.6

关键词： LASER; OSCILLATOR

摘要： We demonstrated a compact and efficient in-band diode-pumped Nd:YVO4 partially end-pumped slab (Innoslab) nanosecond amplifier based on a hybrid reson ...

作者： Tang, H. J.¹;Tian, Z. G.²;Yang, X.¹;Cao, Y.³;Li, W. G.³ （¹ Beijing Inst Technol, Sch Software, Beijing, Peoples R China. ;² Beijing GuangdalongtaiPolytron Technol Inc, Beijing, Peoples R China. ;³ China Japan Friendship Hosp, Dept Nephrol, Beijing 100029, Peoples R China.）

出处： JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS 2016 Vol.30 No.4 P1047-1051

关键词： KIDNEY-DISEASE

摘要： Study has shown that stem cell based therapies are promising strategies in the treatment of several chronic diseases, but their overall benefit in the ...

作者： Li, Jun-Hua¹;Cui, Zhi-Hao¹;Du, Da-Ming¹ （¹ Beijing Inst Technol, Sch Chem Engn & Environm, Beijing 100081, Peoples R China.）

出处： ORGANIC CHEMISTRY FRONTIERS 2016 Vol.3 No.9 P1087-1090

关键词： TERTIARY AMINE CATALYSIS; STEREOGENIC CENTERS; MICHAEL ADDITION; CASCADE REACTION; PYRAZOLONES; SPIROPYRAZOLONES; ORGANOCATALYST; SCAFFOLDS; EDARAVONE; SILVER

摘要： The diastereo- and enantioselective synthesis of cyclohexanone-fused spirospyrazolones containing four consecutive chiral centers has been successfull ...

作者： Lan, Xing-Wang^1,2;Wang, Nai-Xing^1,2;Bai, Cui-Bing^1,2;Lan, Cui-Lan³;Zhang, Tong^1,2;Chen, Shi-Lu³;Xing, Yalan⁴ （¹ Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100190, Peoples R China. ;² Chinese Acad Sci, Univ Chinese Acad Sci, Beijing 100190, Peoples R China. ;³ Beijing Inst Technol, Sch Chem, Beijing 100081, Peoples R China. ;⁴ William Paterson Univ New Jersey, Dept Chem, 300 Pompton Rd, Wayne, NJ 07470 USA.）

出处： ORGANIC LETTERS 2016 Vol.18 No.23 P5986-5989

关键词： METAL-FREE CONDITIONS; C-H BONDS; ACTIVATED ALKENES; ALLYLIC ALCOHOLS; RADICAL-ADDITION; CINNAMIC-ACIDS; COPPER; KETONES; ALPHA; ALKENYLATION

摘要： The first example of a metal-free unactivated C(sp(3))-H bond functionalization of alkyl nitriles with terminal vinylarenes to provide gamma-ketonitri ...

作者： Zhao, Bo-Liang¹;Du, Da-Ming¹ （¹ Beijing Inst Technol, Sch Chem Engn & Environm, Beijing 100081, Peoples R China.）

出处： CHEMICAL COMMUNICATIONS 2016 Vol.52 No.36 P6162-6165

关键词： ALPHA-ALKYLIDENE SUCCINIMIDES; ENANTIOSELECTIVE CONSTRUCTION; 1,3-DIPOLAR CYCLOADDITION; DOMINO REACTIONS; OXINDOLES; ACID

摘要： A bifunctional squaramide-catalyzed Michael/Michael cascade reaction for the construction of five-membered spirooxindoles was developed. This reaction ...

作者： Zhang, Peilong^1,3;Dong, Jiaqiang²;Zhong, Boyu²;Zhang, Deyi²;Yuan, Hongbin²;Jin, Can²;Xu, Xiangyuan²;Li, Hailong²;Zhou, Yong²;Liang, Zhi²;Ji, Minghua²;Xu, Tao²;Song, Guowei²;Zhang, Ling²;Chen, Gang²;Meng, Xuejing²;Sun, Desheng²;Shih, Joe²;Zhang, Ruihao²;Hou, Guojun²;Wang, Chengcheng²;Jin, Ying²;Yang, Qiong² （¹ Beijing Inst Technol, Dept Appl Chem, Zhongguancun South St, Beijing 100081, Peoples R China. ;² Crown Biosci Inc Taicang, 6 Beijing West Rd,Taicang Econ Dev Area, Taicang 215400, Peoples R China. ;³ Beijing Pearl Biotech Ltd, 203,Sect 2, Beijing 100102, Peoples R China.）

出处： BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2016 Vol.26 No.8 P1910-1918

关键词： GENE; IDENTIFICATION; CRIZOTINIB; FUSION

摘要： Anaplastic lymphoma kinase (ALK) is a highly attractive therapeutic target for the treatment of some non-small cell lung cancer patients. This Letter ...

作者： Zhu, Jiaping¹;Jin, Shaohua¹;Yu, Yuehai¹;Wan, Li¹;Li, Lijie¹;Chen, Shusen¹;Shu, Qinghai¹ （¹ Beijing Inst Technol, Sch Mat Sci & Engn, Beijing 100081, Peoples R China.）

出处： ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES 2016 Vol.71 No.3 P197-204

关键词： PERFORMANCE ENERGETIC MATERIALS; QUANTUM-CHEMICAL CALCULATIONS; HIGH-NITROGEN COMPOUND; ATOM CHAINS; DECOMPOSITION; FAMILY; DERIVATIVES; SALTS

摘要： N,N'-Dinitro-4,4'-azo-bis(1,2,4-triazolone) (DNZTO) is synthesized by the reaction of 4,4'-azo-bistriazolone (ZTO) with a mixture of nitric acid and a ...

作者： Tang, Juan¹;Xie, Da¹;Yin, Hao-Yan¹;Jing, Jing²;Zhang, Jun-Long¹ （¹ Peking Univ, Coll Chem & Mol Engn, State Key Lab Rare Earth Mat Chem & Applicat, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China. ;² Beijing Inst Technol, Sch Chem, Beijing 100081, Peoples R China.）

出处： ORGANIC & BIOMOLECULAR CHEMISTRY 2016 Vol.14 No.13 P3360-3368

关键词： EFFECTIVE CORE POTENTIALS; BASE ZINC(II) COMPLEXES; MOLECULAR CALCULATIONS; IMAGING APPLICATIONS; SALPHEN COMPLEXES; IONIC LIQUIDS; LIVE CELLS; IN-VIVO; PROBES; SINGLE

摘要： In this study, we report for the first time that incorporation of cationic sulfonium to the Znsalens skeleton achieves water soluble fluorescent metal ...

作者： Han, Zhongfei¹;Hao, Xin¹;Ma, Bing¹;Zhu, Changjin¹ （¹ Beijing Inst Technol, Dept Appl Chem, 5 Zhongguancun South St, Beijing 100081, Peoples R China.）

出处： EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2016 Vol.121 P308-317

关键词： 5-ARYLIDENE-4-THIAZOLIDINONE DERIVATIVES; QUINOXALINONE DERIVATIVES; ALDEHYDE REDUCTASE; STRUCTURAL ASPECTS; POTENT; ACTIVATION; DESIGN; ENZYME; ACIDS

摘要： A series of pyrido[2,3-b]pyrazin-3(4H)-one based derivatives were designed as inhibitors of aldose reductase (ALR2), the enzyme which plays a key role ...

作者： Yang, Deng-Tao¹;Mellerup, Soren K.¹;Peng, Jin-Bao¹;Wang, Xiang¹;Li, Quan-Song²;Wang, Suning^1,2 （¹ Queens Univ, Dept Chem, Kingston, ON K7L 3N6, Canada. ;² Beijing Inst Technol, Sch Chem, Beijing Key Lab Photoelect Electrophoton Convers, Beijing 100081, Peoples R China.）

出处： JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2016 Vol.138 No.36 P11513-11516

关键词： TRANSITION-METAL-COMPLEXES; STABLE METHYLENEBORANES; ORGANOBORON COMPOUNDS; CONICAL INTERSECTION; OLEFIN METATHESIS; LEWIS ACIDITY; BORON; PHOTOELIMINATION; N,C-CHELATE; CHEMISTRY

摘要： Electron-rich and poor BN-heterocycles with benzyl-pyridyl backbones and two bulky aryls on the boron (Ar = tipp, BN-1, Ar = MesF, BN-2) have been fou ...