作者： Hu, Bo¹;Li, Bo¹²;Li, Kun¹;Liu, Yuanyuan¹³;Li, Chunhui¹;Zheng, Lulu¹;Zhang, Mengjie¹;Yang, Tongren¹;Guo, Shuai¹;Dong, Xiyu³;Zhang, Tian¹;Liu, Qing¹;Hussain, Abid¹;Weng, Yuhua¹;Peng, Ling⁴;Zhao, Yongxiang⁵;Liang, Xingjie⁶;Huang, Yuanyu¹; （¹School of Life Science, Advanced Research Institute of Multidisciplinary Science, Institute of Engineering Medicine, Key Laboratory of Molecular Medicine and Bio-therapy, Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Beijing Institute of Technology, Beijing, 100081, China;²Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, Beijing Institute of Technology, Beijing, 100081, China;³School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, China;⁴Aix-Marseille Université, Center Interdisciplinaire de Nanoscience de Marseille, UMR 7325, Equipe Labellisée Ligue Contre le Cancer, CNRS, Marseille, France;⁵National Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Key Laboratory of Biological Targeting Diagnosis and Therapy Research, Guangxi Medical University, Guangxi, Nanning, 530021, China;⁶Chinese Academy of Sciences (CAS), Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, Beijing, 100190, China）

出处： Science Advances 2022 Vol.8 No.7

摘要： Small interfering RNA (siRNA) therapeutic is considered to be a promising modality for the treatment of hyperlipidemia. Establishment of a thermostabl ...