作者: Rasheed, Madiha;|Wang, Han;|Wang, Chaolei;|Sun, Jingyan;|Chen, Zixuan;|Deng, Yulin (1Beijing key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Sciences, Beijing Institute of Technology)
出处: Journal of Neurochemistry 2023 P1
关键词: depression;microgravity;miRNA‐455‐3p;neuroprotection;NR2B‐PSD‐95‐nNOS complex;simulated space complex environment
摘要: Depression in astronauts is one of the consequences of space flight effects, negatively impacting their work performances. Unfortunately, the underlyi ...
作者: Ma, Yunqing;|Chen, Songhao;|Chen, Duanduan (1Department of Orthopaedics, The Fourth Medical Center of PLA General Hospital 2School of Life Science, Beijing Institute of Technology 3Key Laboratory of Convergence Medical Engineering System and Healthcare Technology, The Ministry of Industry and Information Technology, Beijing Institute of Technology)
出处: International Journal for Numerical Methods in Biomedical Engineering 2023 P1
关键词: finite element analysis;periacetabular osteotomy;stress distribution;total hip replacement
摘要: Periacetabular osteotomy (PAO) is an effective technique to treat symptomatic hip dysplasia. However, following PAO, some patients still experience pe ...
作者: Weibo Zhao;Yanbo Zeng;Wenjun Chang;Huiqin Chen;Hao Wang;Haofu Dai;Fang Lv (1 Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China. 2 Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences & Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Hainan Institute for Tropical Agricultural Resources, Haikou 571101, China. 3 Zhanjiang Experimental Station of Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524013, China.)
出处: Marine drugs 2023 Vol.21 No.3 P157
关键词: Aspergillus insulicola;ECD calculations;marine fungus;phenolic compounds;α-glucosidase inhibition.
摘要: Three new phenolic compounds, epicocconigrones C-D ( 1 - 2 ) and flavimycin C ( 3 ), together with six known phenolic compounds: epicocconigrone A ( 4 ...
作者: Yanbo Zeng;Zhi Wang;Wenjun Chang;Weibo Zhao;Hao Wang;Huiqin Chen;Haofu Dai;Fang Lv (1 Hainan Provincial Key Laboratory for Functional Components Research and Utilization of Marine Bio-resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences & Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Hainan Institute for Tropical Agricultural Resources, Haikou 571101, China. 2 Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceuticals, School of Life Science, Beijing Institute of Technology, Beijing 100081, China. 3 Zhanjiang Experimental Station of Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524013, China.)
出处: Marine drugs 2023 Vol.21 No.2 P75
关键词: Penicillium sclerotiorum;anti-inflammatory activity;antitumor activity;azaphilones;marine-derived fungus;structure elucidation.
摘要: Nine new azaphilones, including penicilazaphilones I-N (1, 2 and 6-9), epi-geumsanol D (3) and penidioxolanes C (4) and D (5) were isolated from the c ...
作者: Xiao-Kang Shang;Si-Meng Zhang;Jun-Jun Ni (1 Key Laboratory of Molecular Medicine and Biotherapy, School of Life Science, Beijing Institute of Technology, Beijing 100081, China.)
出处: Yi chuan = Hereditas 2023 Vol.45 No.3 P212-220
关键词: Alzheimer’s disease;aging;cathepsin B;microglia;neuron.
摘要: Cathepsin B (CatB), a cysteine protease derived from lysosomes, was initially thought to non-selectively degrade proteins from phagocytosis and autoph ...
作者: Yinfeng Zhang;Tingting Wang;Meng Sun;Yueyue Song;Xinyuan Huang;Shutian Zhang;Jun Yang;Jinfeng Zhang (1 Department of Gastroenterology, Beijing Friendship Hospital, National Clinical Research Center for Digestive Disease, Beijing Key Laboratory for Precancerous Lesion of Digestive Diseases, Capital Medical University, Beijing, 100050, P. R. China. 2 International Medical Center, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, P. R. China. 3 Key Laboratory of Molecular Medicine and Biotherapy, School of Life Sciences, Beijing Institute of Technology, Beijing, 100081, P. R. China. 4 Beijing Institutes of Pharmacology and Toxicology.)
出处: Advanced healthcare materials 2023 Pe2300069
关键词: Inflammatory bowel disease (IBD);gut microbiota;macrophage polarization;nanotherapeutics;reactive oxygen species (ROS).
摘要: Inflammatory bowel disease (IBD), a chronic and recurrent gastrointestinal inflammatory disorder with a variety of painful clinical manifestations and ...
作者: Zhang, Jin-wei1;Xu, Ke2,3;Gao, Xiao-peng4;Zhang, Yun-feng3;Guo, Dong-yu3;Qin, Lei2;Ashraf, Munaza5;Ahmad, Nadeem6;Li, Chun1,2; (1 Inst Biochem Engn, Beijing Inst Technol, Sch Chem & Chem Engn, Key Lab Med Mol Sci & Pharmaceut Engn,Minist Ind &, Beijing, Peoples R China. ;2 Tsinghua Univ, Dept Chem Engn, Key Lab Ind Biocatalysis, Minist Educ, Beijing, Peoples R China. ;3 Tangshan Normal Univ, Dept Life Sci, Key Lab Agr Pathogen Fungi & Toxins, Tangshan, Peoples R China. ;4 Yanan Univ, Sch Life Sci, Yanan, Shanxi, Peoples R China. ;5 Univ Sargodha, Dept Zool, Sargodha, Pakistan. ;6 COMSATS Univ Islamabad, Dept Pharm, Abbottabad Campus, Abbottabad, Pakistan.)
出处: BIOTECHNOLOGY AND BIOENGINEERING 2023 Vol.120 No.3 P860-860
作者: Zhang, Jian1; Zhang, Zesen2; Jiang, Ting1; Zhang, Zhenyu2; Zhang, Wenjing1; Xu, Wei1 (1School of Life Science, Beijing Institute of Technology, No.5 Yard, Zhongguancun South Street, Haidian District, Beijing; 100081, China;2State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Zhongguancun Street, Hai Dian District, Beijing; 100084, China)
出处: SSRN 2023
作者: Xie, Zhen1;Zhao, Mengyuan1;Yan, Chengxiang2;Kong, Wei1;Lan, Fei1;Narengaowa1;Zhao, Shuxuan1;Yang, Qinghu2;Bai, Zhantao23;Qing, Hong1;Ni, Junjun1; (1Key Laboratory of Molecular Medicine and Biotherapy, Department of Biology, School of Life Science, Beijing Institute of Technology, Beijing, 100081, China;2Research Center for Resource Peptide Drugs, Shaanxi Engineering and Technological Research Center for Conversation and Utilization of Regional Biological Resources, Yan’an University, Yan’an, 716000, China;3Yan’an Key Laboratory for Neural Immuno-Tumor and Stem Cell and Engineering and Technological Research Center for Natural Peptide Drugs, Yan’an, 716000, China)
出处: Cell death & disease 2023 Vol.14 No.4 P255
摘要: Cathepsin B (CatB), a cysteine protease, is primarily localized within subcellular endosomal and lysosomal compartments. It is involved in the turnove ...
作者: Sun, Zhigao1;Ping, Ping2;Zhang, Pei3;Yao, Yao45;Huang, Zhenjun1;Zhao, Yali6;Luo, Leiming7;Fu, Shihui78; (1Traditional Chinese Medicine Department, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, China;2General Station for Drug and Instrument Supervision and Control, Joint Logistic Support Force of Chinese People's Liberation Army, Beijing, China;3School of Life Science, Beijing Institute of Technology, Beijing, China;4Center for the Study of Aging and Human Development and Geriatrics Division, Medical School of Duke University, NC, United States;5Center for Healthy Aging and Development Studies, National School of Development, Peking University, Beijing, China;6Central Laboratory, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, China;7Department of Geriatric Cardiology, Chinese People's Liberation Army General Hospital, Beijing, China;8Department of Cardiology, Hainan Hospital of Chinese People's Liberation Army General Hospital, Sanya, China)
出处: Heliyon 2023 Vol.9 No.2
摘要: Background: Depressive disorder is a common comorbidity in patients with cardiovascular diseases and is associated with increased hospitalization and ...