作者： 张凯^1,2;，徐元媛¹;，高尚¹;，李加荣³; （¹石家庄学院；²石家庄市靶点药物研究与药效学评价重点实验室；³北京理工大学）

出处： 现代农药 2024 第23卷 第2期 P39-44

关键词： 乙基多杀菌素；多杀霉素；研究进展

摘要： 多杀菌素类化合物是一类新型高效的生物源杀虫剂，对多种害虫具有显著的活性抑制作用。多杀霉素（spinosad）和乙基多杀菌素（spinetoram）为多杀菌素类化合物第1代和第2代商业化产品，具有杀虫活性高、降解速度快、对环境友好以及对非靶标生物毒性低等特点。本文着重对乙基多杀菌素的理化性质、杀虫机制 ...

作者： Duan,Jianyu¹;Zhang,Qi¹;Su,Ziqi¹;Xu,Juan²;Yang,Junjuan³;Li,Jiarong¹; （¹School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, China;²National Research Institute for Family Planning, Haidian District, No.12, Da Hui Si Road, Beijing, 100081, China;³Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Colloid and Interface and Thermodynamics, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, China）

出处： Current Organic Chemistry 2023 Vol.27 No.9 P759-771

摘要： Since the discovery of the new conversion, through intramolecular Pinner to Dimroth rearrangement to form a new skeleton product of dihydroquinazolino ...

作者： Kai Zhang^{1   2};Yuanyuan Xu¹;Shang Gao¹;Jiarong Li³; （¹ School of Chemical Engineering, Shijiazhuang University, Shijiazhuang, Hebei, China. ² Shijiazhuang Key Laboratory of Target Drug Research and Pharmacodynamic Evaluation, Shijiazhuang, Hebei, China. ³ School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, China.）

出处： Natural product research 2023 P1-13

关键词： Spinetoram;derivatization;insecticidal activity;synthesis.

摘要： As the second generation commercial product of spinosyns, spinetoram not only has obvious insecticidal effect on vegetable crops, but also can effecti ...

作者： Yiyun Wang¹;Jiaru Wang¹;Hui Wu²;Longyao Cui²;Zihui Meng¹;Zhibin Xu¹;Zhonghui Zheng²;Jiarong Li¹; （¹School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China;²Shandong Xinhua Pharmaceutical Co., Ltd., No.¹Lutai Avenue, Zibo 255086, China）

出处： Crystals 2023 Vol.13 No.988 P988

关键词： baloxavir;derivatives;synthesis;inhibition

摘要： Baloxavir marboxil is a creative antiviral drug for influenza A and B viruses with a novel mechanism of action. In this study, three series comprising ...

作者： 张凯¹;高尚¹;李加荣² （¹石家庄学院化工学院, 河北, 石家庄, 050000;²北京理工大学化学与化工学院, 北京, 100081）

出处： 火工品 2022 第4期 P43-48

关键词： 气体发生剂；有机盐；合成；稳定性；爆轰性能

摘要： 为获得性能优异、绿色环保的新型气体发生剂,以高氮含能离子盐3-硝基-1,2,4-三唑-5-酮(NTO)为阴离子,分别合成了3种NTO有机盐,对其结构进行了表征,并对其热稳定性、感度以及爆轰性能进行了测试和计算。结果表明3种NTO有机盐均具有较好的热稳定性、较低的感度以及优异的爆轰性能,有望应用于气体 ...

作者： Na Wang¹;Yaxin Guo¹;Jiarong Li¹;Shufeng Pang¹;CA1;Yunhong Zhang¹;CA2 （¹School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, PR China）

出处： Atmospheric Environment 2022 Vol.273 No.0 P118951

关键词： Amino acid;Ammonium nitrate;ATR-FTIR;Hygroscopic properties;Microscopy technology

摘要： Water-soluble amino acids have been confirmed as effective cloud condensation nuclei (CCN) materials. While their influence on the hygroscopicity of n ...

作者： Ye,Xinming¹²³;Zhang,Xiaolian⁴;Jiang,Yunyun⁵;Qiao,Liang¹;Zhang,Wenchao¹;Pan,Ye-Tang¹;Yang,Rongjie¹;Li,Jiarong²;Li,Yingchun³; （¹National Engineering Technology Research Center of Flame Retardant Material, School of Materials, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing, 100081, China;²School of Chemistry and Chemical Engineering, Beijing Institute of Technology, 5 South Zhongguancun Street, Haidian District, Beijing, 100081, China;³School of Materials Science and Engineering, North University of China, No.;³Xueyuan Road, Taiyuan, 030051, Shanxi Province, China;⁴Marine Chemical Research Institute, No. 4, Jinhu Road, Qingdao, 266071, Shandong Province, China;⁵China Wuzhou Engineering Group Corporation LTD., 85 Xibianmen Nei Dajie, Xicheng District, Beijing, 100032, China）

出处： Composites Part B: Engineering 2022 Vol.229

摘要： Mitigating the fire hazards of epoxy resin (EP) and simultaneously improving mechanical properties have always been a goal pursued by polymeric scient ...

作者： Wang,Na¹;Guo,Yaxin¹;Li,Jiarong¹;Pang,Shufeng¹;Zhang,Yunhong¹; （¹School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, China）

出处： Atmospheric Environment 2022 Vol.273

摘要： Water-soluble amino acids have been confirmed as effective cloud condensation nuclei (CCN) materials. While their influence on the hygroscopicity of n ...

作者： Yiyun Wang;Youwei Xu;Zhonghui Zheng;Min Xue;Zihui Meng;Zhibin Xu;Jiarong Li;Qing Lin （¹School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 102488, China;²Shandong Xinhua Pharmaceutical Co., Ltd., Zibo 255086, China;³ReadCrystal Biotech Co., Ltd., Suzhou 215505, China）

出处： Crystals 2022 Vol.12 No.7 P917

关键词： Parkinson’s disease;istradefylline;solubility;crystal form;dissolution

摘要： Istradefylline as a selective adenosine A_2A-receptor antagonist is clinically used to treat Parkinson’s disease and improve dysk ...

作者： Yiyun Wang;Xiaofang Lv;Zihui Meng;Zhibin Xu;Zhonghui Zheng;Jiarong Li;Min Xue （¹ School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China ² Shandong Xinhua Pharmaceutical Co., Ltd., No.1 Lutai Avenue, Zibo 255086, China Authors to whom correspondence should be addressed.）

出处： Crystals 2022 Vol.12 No.7 P891

关键词： baloxavir marboxil;intermediate;synthesis;sulfonate resin solid acid;microwave irradiation

摘要： The compound (±)-12aR-12-[(11S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl]-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrid ...