作者：Feiran Liu¹;Xiaoli Zhang²;Jing Jing¹;CA1;Xiaoling Zhang^1,2;CA2 （¹Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Key Laboratory of Cluster Science of Ministry of Education, Beijing Key Laboratory of Photo-electronic/Electrophotonic Conversion Materials, Analytical and Testing Center, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, PR China;²School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, PR China）

出处：Dyes and Pigments 2023

摘要：Golgi stress was the major stress response in the Golgi apparatus, which might be induced the disruption of redox balance and relate to a variety of d ...

作者：Rubing Han¹;Jin Yu¹;Yunpeng Wang¹;Yuru Chen¹;Xiaoli Zhang¹;Rubo Zhang¹;1;Jing Jing^1,2;2;Xiaoling Zhang^1,2;3 （¹Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Ministry of Industry and Information Technology, Key Laboratory of Cluster Science of Ministry of Education, Beijing Key Laboratory of Photo-electronic/Electrophotonic Conversion Materials, Analytical and Testing Center, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081, P. R. China;²School of Medical Technology, Beijing Institute of Technology, Beijing, 100081, P. R. China）

出处：Sensors and Actuators B: Chemical 2023

摘要：Parkinson\'s disease (PD) is a neurodegenerative disease common in middle-aged and older individuals. At present, the exact cause is unknown, and the ...

作者：刘飞冉¹;，敬静¹;，张小玲^1,2; （¹北京理工大学化学与化工学院；²北京理工大学医学技术学院）

出处：有机化学 2023

关键词：半胱氨酸；细胞器；靶向定位；荧光探针

摘要：半胱氨酸作为一种重要的内源性小分子硫醇,参与众多生理过程,对细胞内氧化还原水平的调节和生物活性物质的合成具有重要意义.细胞器在生命过程中发挥着不可或缺的作用,不同细胞器具有各自独特的功能,而半胱氨酸在不同细胞器内的作用机制不尽相同.荧光探针的高灵敏度与原位检测能力提供了研究不同细胞器内半胱氨酸的方法 ...

发明人：敬静，康浩，张小玲

申请日期：2023.02.08

摘要：本发明涉及一种用于内质网中HNO检测的双光子荧光探针及其制备方法和应用，属于生物化学分析技术领域。本发明的双光子荧光探针,通过810nm激光对探针进行激发，实现内质网中HNO浓度的检测，可应用于帕金森病模型的早期诊断；本发明的双光子荧光探针，通过飞秒激光激发可以降低背景，延长激发波长，从而适合活体脑 ...

发明人：董利，墨越，张小玲，权恒道

申请日期：2022.11.15

摘要：本申请提供了一种从非共沸组合物中回收1,1,2,2,3,3,4‑七氟环戊烷的方法，所述非共沸组合物为叔戊醇、苯甲醇和1,1,2,2,3,3,4‑七氟环戊烷的非共沸物组合物，其中，非共沸组合物在催化剂作用下叔戊醇发生脱水反应，通过精馏得到1,1,2,2,3,3,4‑七氟环戊烷馏分；1,1,2,2,3, ...

作者：Shu, Wei¹; Yu, Jin²; Li, Zhuohang¹; Sun, Xiaoqian¹; Wang, Yunpeng²; Wu, Yulong³; Qin, Jie¹; Zhang, Yu¹; Xiao, Haibin⁴; Zhang, Xiaoling²; （¹School of Life Sciences and Medicine, Shandong University of Technology, Zibo; 255000, China;²Key Laboratory of Cluster Science of Ministry of Education, Beijing Key Laboratory of Photo-electronic/Electrophotonic Conversion Materials, Analytical and Testing Center, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing; 100081, China;³Department of Radiochemistry, China Institute of Atomic Energy, Beijing; 102413, China;⁴School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo; 255000, China）

出处：Sensors and Actuators B: Chemical 2022

关键词：Fluorescent probe;Ratiometric;pH;Bioimaging;Mitophagy

摘要：Intracellular pH is one of the important parameters of cellular metabolism. The function of mitochondria is highly dependent on pH. Developing ratiome ...

作者：Cui, Jie^{1, 2}; Nie, Hailiang¹; Liang, Xiaomeng¹; Bai, Jie¹; Zhang, Xiaoling²; （¹Key Laboratory of Public Health Safety of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, School of Public Health, Hebei University, Baoding; 071002, China;²Key Laboratory of Cluster Science of Ministry of Education, Beijing Key Laboratory of Photo-electronic/Electrophotonic Conversion Materials, Analytical and Testing Center, School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing; 100081, China）

出处：Journal of Molecular Liquids 2022

关键词：Fluorescent probe;pH;Ratiometric;Pyrene;Excimer

摘要：Acidity in biological microenvironments plays a crucial role in physiology and pathology, so that pH monitoring can provide insights into the mechanis ...

作者：Wang, Dongjie¹; Kang, Jingrong¹; Zhang, Zheling^{1, 2}; Zhu, Guisheng¹; Zhang, Xiaoling²; Xiong, Jian¹; Zhang, Jian¹; （¹Engineering Research Center of Electronic Information Materials and Devices (Ministry of Education), Guangxi Key Laboratory of Information Materials, School of Materials Science and Engineering, Guilin University of Electronic Technology, Guilin; 541004, China;²Key Laboratory of Cluster Science (Ministry of Education), School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing; 100081, China）

出处：Materials Letters 2022

关键词：Semiconductors;Solar energy materials;Titanium dioxide;Perovskite

摘要：Titanium dioxide (TiO2) is commonly used in high-performance carbon-based mesoscopic perovskite solar cells (C-MPSCs), but its relatively low charge m ...

作者：Fanrong Chen;Xiaoying Lu;Liang Ding;Zhen-Hua Lyu;Xiaoling Zhang;Jiaju Fu;Jin-Song Hu （School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China Shaanxi Key Laboratory of Chemical Reaction Engineering, College of Chemistry & Chemical Engineering, Yan\'an University, Yan\'an, 716000 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China University of Chinese Academy of Sciences, Beijing, 100049 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China University of Chinese Academy of Sciences, Beijing, 100049 P. R. China School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, 100081 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China Beijing National Laboratory for Molecular Sciences (BNLMS), Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190 P. R. China University of Chinese Academy of Sciences, Beijing, 100049 P. R. China）

出处：Small Methods 2024

关键词：CuInS2 quantum dots;electrocatalytic CO2 reduction;high-density active sites;high-performance electrocatalysts;long-term durability

摘要：Electrochemically converting CO₂ back into fuels and chemicals is promising in alleviating the greenhouse effect worldwide. Various high-ef ...

发明人：韩杰，张小玲

申请日期：2024.05.08

摘要：本发明涉及一种双通道检测细菌感染的荧光探针及其制备方法和应用，属于细菌感染的检测和治疗技术领域，具体是一种双机制响应双通道精准检测细菌感染及光动力治疗荧光探针的制备和应用。本发明制备了一种双机制响应的荧光探针，在单一激发光下可以实现双发射通道无串扰的荧光检测，同时，探针对细菌具有单一的靶向性而不进入 ...