发明人：冯旭东，孙秋艳，孟亮旗，刘护，李春

申请日期：2024.04.11

摘要：发明“三个UDP‑糖基转移酶及其在合成齐墩果酸糖苷化合物中的应用”属于生物工程与技术领域。本发明提供一种UDP‑糖基转移酶，涉及三个来源于油橄榄的UDP‑糖基转移酶Oe440、Oe139、Oe535，实现在齐墩果酸C28‑COOH特异性修饰一分子糖基生成28‑氧‑葡萄糖‑齐墩果酸；提供了一株工程化酿 ...

作者：Jin, Hong-Jie^a,b;Niu, Yu-Jing^a,c;Cao, Hong¹;CAa;Li, Chun⁴;Luo, Ting¹;Shen, Rui-Lin¹; （¹College of Biological and Chemical Sciences and Engineering, Jiaxing University, Zhejiang, Jiaxing, 314001, China;²College of Life Sciences, Shihezi University, Shihezi, Xinjiang, 832003, China;³Food Science College, Shihezi University, Shihezi, Xinjiang, 832003, China;⁴School of Life Sciences, Beijing Institute of Technology, Beijing, 100081, China）

出处：Mycosystema 2019

关键词：fermentation conditions;Penicillium purpurogenum;red pigment;response surface methodology;zebrafish

摘要：The fermentation conditions and red pigment safety of Penicillium purpurogenum Li-3-9 were investigated. On the basis of single factor test, the Box-B ...

发明人：李春，张亚鹏，吕波，秦磊

申请日期：2024.05.23

摘要：本发明涉及基因工程领域，具体涉及生产石竹烯的基因工程菌株及其构建方法。该基因工程菌株的出发菌株为酿酒酵母；在基因工程菌株的基因组中，第一基因的内源启动子被替换为第一启动子，其中第一基因选自由ERG9、ERG1、ERG7和ERG11组成的组；第一启动子独立地选自由以下组成的组：P_ERG1

作者：Xing Jian¹;Qiuyan Sun¹;Wentao Xu¹;Haobo Qu¹;Xudong Feng¹;Chun Li²; （¹ Beijing Institute of Technology, Department of Biochemical Engineering, No 5, Zhongguancun South Street, 100081, Beijing, CHINA. ² Tsinghua University, Department of Chemical Engineering, 100084, Beijing, CHINA.）

出处：Angewandte Chemie (International ed. in English) 2024

关键词：UDP-glycosyltransferase;biocatalysis;protein engineering;reconstructed ancestral enzyme;triterpenoid 2"-O-glycosylation.

摘要：Triterpenoids have wide applications in the pharmaceutical and agricultural industries. The glycosylation of triterpenoids catalyzed by UDP-glycosyltr ...